Modafinil: a Look at the Brief History of Modafinil - Inspire Me

Modafinil: a Look at the Brief History of Modafinil

Modafinil is a eugeroic medication, which means it’s a wakefulness-promoting pill. It’s the central nervous system (CNS) stimulant medication used mainly to help people strengthen concentration, combat fatigue, and remain active. As stimulants, it’s not as powerful as the amphetamine but it does have similar effects as the more effective drugs, only at a limited intense level of CNS arousal. Modafinil 200 is used clinically to ease conditions that include sleep disorders and narcolepsy. Hence, it helps people who suffer from excessive daytime sleepiness, sleep apnea, and shift work sleep disorder. Shift work sleep disorder is the sleep condition caused by having a work schedule that’s out of sync with your daily sleep/wake cycle. Modafinil also has off-label uses as cognitive enhancers. It helps people to aim their attention. Also, it has been used to relieve excessive fatigue related to medical conditions like Parkinson’s disease, cancer, or sclerosis.

There’s evidence that modafinil may be useful as an assistive drug added to antidepressant medications in the alleviation of severe depression. As you might expect, the drug has also been used as an off-label medication to assist the treatment of ADHD. There has been some interest for its potential uses in the military, for astronauts, or for airline pilots as the result of its ability to promote energy and wakefulness; hence, increasing concentration.

The Brief History of Modafinil

According to experts, modafinil was originally developed in the 1970s in France in which an early study was carried out, and then the drug was found to be an effective medication for narcolepsy. The last clinical study was carried out in 1986 concluding that the pill wasn’t only effective for treating narcolepsy and other sleep disorders but also reduced the need for sleep in healthy people. The drug received FDA approval in 1998 and was manufactured under the brand name Provigil in the US. Modafinil experience Reddit was comfortable.

Modafinil is sold under different brand names. For instance, in HongKong, the UK, the US, or other states, it’s sold under the brand name Provigil. In Japan and France, it’s manufactured under the name Modiodal. In Switzerland, it’s sold under the brand name Modasomil. The pill is manufactured by Cephalon, Inc., and there’s an FDA-approved generic version.

Mechanism of Action

According to experts, the exact mechanism by which modafinil work is unclear at this time; still, it’s thought that the drug activates the synthesis of a class of neurotransmitters called monoamines that include the neurotransmitters: serotonin, noradrenaline, or dopamine. It is suggested that this may be the main action of modafinil that contributors to its clinical effects. Eugeroic form treatments also include similar pills that include armodafinil (Nuvigil) and adrafinil (Olmifon).

Modafinil is taken in tablet form and the tablets are sold in 100 mg and 200 mg doses. The recommended dosage for treatment in people with excessive sleepiness or narcolepsy due to obstructive sleep apnea is 200 mg once a day, commonly taken in the morning. The same dosage is recommended for people with shift work sleep disorder, except that’s prescribed that the medication is to be taken one hour before work. Visit that site to learn more!

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